International Journal of Modern Science and Technology

INDEXED IN 

​​​​​​​​​​​​​April 2018, Vol. 3, No. 4, pp 90-97. 

​​​Studies on phytochemical constituents, antioxidant and anti-inflammatory activities of Annona reticulata peel extracts

J. Iyyappan¹,*, S. Rohinipriya¹, B. Bharathiraja¹, G. Baskar²
¹Vel Tech High Tech Dr. Rangarajan Dr. Sakunthala Engineering College, Chennai - 600062. India.
²Department of Biotechnology, St. Joseph’s College of Engineering, Chennai - 600119. India.
​​​*Corresponding author’s e-mail: jiyyappan.biotek@gmail.com

​Abstract

​In the present work, Annona reticulata fruit peel extracts were investigated for antioxidant and anti-inflammatory activities. The peel extracts of Annona reticulata were acquired by using different solvent systems. Total phenolic contents were estimated by Folin–Ciocalteau method and flavonoid content were measured by aluminum chloride method. Proximate analysis such as total protein, carbohydrate, ash, and moisture contents were also carried out by standard methods. The plant extracts were analyzed by GC-MS method and simultaneously antioxidant activity was investigated by DPPH (1, 1-diphenyl-2-picrylhydrazyl) assay. Anti-inflammatory activity was also explored. Among five different solvents used, the maximum antioxidant activity and anti-inflammatory activity was found in ethanol extract followed by others. The total phenol and flavonoid content in peel extract were found to be 20.14 mg gallic acid equivalents (GAE)/g and 5.58+1.98 mg Quercetin Equivalent (QE)/g respectively. Thus, Annona reticulata fruit peel could serve as best lead composite for manipulating a persuasive anti-oxidant and anti-inflammatory drug.

Keywords: Annona reticulata fruit peel; Extraction; Antioxidant and anti-inflammatory activity; Compound identification.

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